Mono Symptoms Usually Appear 4 to 8 Weeks after One is Infected with EBV

Mono symptoms are formally known as infectious mononucleosis and it is caused by the Epstein-Barr virus (EBV). This disease is also known as the “kissing disease” because kissing is one of the common methods of transferring the disease. Almost everyone is affected by EBV at one point of their lives, but not everyone gets mononucleosis.

Mono Symptoms

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Research has shown in those ages 5-30 that only 10% with those with EVB get mono symptoms. Mononucleosis however, is more common in college students. Older people generally do not get mononucleosis often unless they have a compromised immune system.

Common symptoms that those with mononucleosis have can include a sore throat, general fatigue, swollen lymph nodes on the sides and back of neck, above the groin, and under the armpits. A fever that can reach 105F may be present and it can peak at the highest temperature in the early evening or late afternoon.

Mono signs usually appear four to eight weeks after one is infected with EBV. Before the symptoms arrive, one may feel generally ill for a week. The infection tends to last between 1 to 3 weeks. However, a small percentage of people have fatigue that can last for a while longer.

EBV will remain infectious in the body for several months after the infection, which can cause the bacteria to spread to other people. EBV does not completely leave the body after this infectious period is over.

It is important to note that not everyone has the usual mononucleosis symptoms. Many people just have swollen lymph nodes and some people have no symptoms at all! Others may just feel generally tired. In younger children, they tend to experience just a sore throat or tonsillitis.

Mononucleosis also causes the liver to swell in 20% of those infected and spleen enlargement in 50% of those infected. It is recommended to not do heavy lifting or sports for a few months because of the delicate spleen. Strain to the spleen can cause rupturing.

In very rare cases, some people might have jaundice. Jaundice is a medical condition that is caused by liver damage. Jaundice causes the bile in the liver to be backed up into the blood stream, causing the skin and the whites of one’s eyes to turn yellow. If you notice this symptom, it is important to see a doctor right away. Other rare problems include brain inflammation (encephalitis).

If you are experiencing more severe symptoms, it is important to see your doctor.

YouTube Video

Mono: The Makeout Disease (College Health Guru)


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